ISSN: 1309 - 3843 E-ISSN: 1307 - 7384
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Tedaviye Uyumun Önemini Gözler Önüne Seren Bir Olgu: Evsiz Bir Romatoid Artrit Hastasında Gelişen Servikal Subluksasyon
A Case That Reveals the Importance of Adherence to Treatment: Development of Cervical Subluxation in a Homeless Rheumatoid Arthritis Patient
Received Date : 15 Jan 2018
Accepted Date : 12 Mar 2018
Doi: 10.31609/jpmrs.2018-59759 - Makale Dili: TR
J PMR Sci. 2019;22(2):80-4
ÖZET
Romatoid artrit; toplumun yaklaşık %1’ini etkileyen sistemik, kronik, inflamatuar bir hastalıktır. Tuttuğu eklemlerde destrüksiyonla seyretmektedir. En sık el, ayak ve servikal bölgedeki eklemleri etkilemektedir. Klinik olarak nörolojik defisit, ölüm gibi ciddi sonuçlara yol açan servikal omurga tutulumu için bazı risk faktörleri bulunmaktadır. Yüksek hastalık aktivitesi de bunlardan biridir. Metotreksat başta olmak üzere, hastalık modifiye edici antiromatizmal ilaçlar romatoid artrit aktivitesini baskılamakta, eklem destrüksiyonlarını azaltmakta ve servikal omurga tutulumu gibi ciddi komplikasyonları önleyebilmektedir. Ancak, bu tedavinin başarıya ulaşabilmesi için hastanın tedaviye uyumu ve sıkı takip gerekmektedir. Tedaviye uyumu olumlu ve olumsuz etkileyen birçok faktör saptanmıştır. Düşük sosyoekonomik düzey bu olumsuz faktörlerin başında gelmektedir. Bu çalışmada, 16 yıl önce romatoid artrit tanısı almış ama tedaviye devam edememiş evsiz bir olguda gelişen atlantoaksiyel subluksasyon ve tetraparezi kliniği ile rehabilitasyonunun anlatılması amaçlanmıştır.
ABSTRACT
Rheumatoid arthritis; is a systemic, chronic, inflammatory disease affecting approximately 1% of the population. It affects destruction in joints. Most commonly affect joints in the hands, feet and cervical region. Cervical spine involvement leads to clinically serious consequences such as neurological deficit, death. There are some risk factors for cervical spine involvement. High disease activity is one of them. Disease-modifying anti-rheumatic drugs, especially methotrexate, suppress rheumatoid arthritis activity, reduce joint destruction, and prevent serious complications such as cervical spine involvement. However, compliance with the treatment of the patient and strict follow-up is essential for this treatment to be successful. A number of factors have been identified that affect treatment compliance in a positive and negative way. Low socioeconomic level is one of these negative factors. In this case; atlanto-axial subluxation, post-operative tetraparesis clinic and rehabilitation was described in a homeless patient who had been diagnosed with rheumatoid arthritis 16 years ago.
REFERENCES
  1. Joaquim AF, Appenzeller S. Cervical spine involvement in rheumatoid arthritis--a systematic review. Autoimmun Rev. 2014;13:1195-202. [Crossref] 
  2. Nguyen HV, Ludwig SC, Silber J, et al. Rheumatoid arthritis of the cervical spine. Spine J. 2004;4:329-34. [Crossref]  [PubMed] 
  3. Wasserman BR, Moskovich R, Razi AE. Rheumatoid arthritis of the cervical spine--clinical considerations. Bull NYU Hosp Jt Dis. 2011;69:136-48.
  4. Manczak M, Gasik R. Cervical spine instability in the course of rheumatoid arthritis-imaging methods. Reumatologia. 2017;55:201-7. [Crossref]  [PubMed]  [PMC] 
  5. Na MK, Chun HJ, Bak KH, et al. Risk factors for the development and progression of atlantoaxial subluxation in surgically treated rheumatoid arthritis patients, considering the time interval between rheumatoid arthritis diagnosis and surgery. J Korean Neurosurg Soc. 2016;59:590-6. [Crossref]  [PubMed]  [PMC] 
  6. Vanek P, Bradac O, de Lacy P, et al. Treatment of atlanto-axial subluxation secondary to rheumatoid arthritis by short segment stabilization with polyaxial screws. Acta Neurochir (Wien). 2017;159: 1791-801. [Crossref]  [PubMed] 
  7. Arshad N, Ahmad NM, Saeed MA, et al. Adherence to methotrexate therapy in rheumatoid arthritis. Pak J Med Sci. 2016;32:413-7.
  8. Cannon GW, Mikuls TR, Hayden CL, et al. Merging Veterans Affairs rheumatoid arthritis registry and pharmacy data to assess methotrexate adherence and disease activity in clinical practice. Arthritis Care Res (Hoboken). 2011;63:1680-90. [Crossref]  [PubMed]  [PMC] 
  9. Ahluwalia V, Rampakakis E, Movahedi M, et al. Predictors of patient decision to discontinue antirheumatic medication in patients with rheumatoid arthritis: results from the Ontario best practices research initiative. Clin Rheumatol. 2017;36:2421- 30. [Crossref]  [PubMed] 
  10. Zhu S, Xu W, Luo Y, et al. Cervical spine involvement risk factors in rheumatoid arthritis: a metaanalysis. Int J Rheum Dis. 2017;20:541-9. [Crossref]  [PubMed] 
  11. Yurube T, Sumi M, Nishida K ve ark. Accelerated development of cervical spine instabilities in rheumatoid arthritis: a prospectiveminimum 5-year cohort study. PLoS One. 2014;9:e88970. [Crossref]  [PubMed]  [PMC] 
  12. Sendur O, Turan Y. Romatoid artritte omurga tutulumu. Turk Fiz Tip Rehab Derg. 2008;54:15- 9.
  13. Kaito T, Ohshima S, Fujiwara H, et al. Incidence and risk factors for cervical lesions in patients with rheumatoid arthritis under the current pharmacologic treatment paradigm. Mod Rheumatol. 2017;27:593-7. [Crossref]  [PubMed] 
  14. Kauppi MJ, Neva MH, Laiho K, et al. Rheumatoid atlantoaxial subluxation can be prevented by intensive use of traditional diseasemodifying antirheumatic drugs. J Rheumatol. 2009;36:273-8. [Crossref]  [PubMed] 
  15. Kaito T, Hosono N, Ohshima S, et al. Effect of biological agents on cervical spine lesions in rheumatoid arthritis. Spine (Phila Pa 1976). 2012;37:1742-6. [Crossref]  [PubMed] 
  16. Kaito T, Ohshima S, Fujiwara H, et al. Predictors for the progression of cervical lesion in rheumatoid arthritis under the treatment of biological agents. Spine (Phila Pa 1976). 2013;38:2258-63. [Crossref]  [PubMed] 
  17. Mena-Vazquez N, Manrique-Arija S, YunqueraRomero L, et al. Adherence of rheumatoid arthritis patients to biologic disease-modifying antirheumatic drugs: a cross-sectional study. Rheumatol Int. 2017;37:1709-18. [Crossref]  [PubMed] 
  18. Marras C, Monteagudo I, Salvador G, et al. Identification of patients at risk of non-adherence to oral antirheumatic drugs in rheumatoidarthritis using the Compliance Questionnaire in Rheumatology: an ARCO sub-study. Rheumatol Int. 2017;37:1195-202. [Crossref]  [PubMed]